The 153rd WPI-IIIS seminar

EVENTS

Date	Tuesday, July 9, 2019
Time	12:00 -13:00
Venue	1F Auditorium, IIIS Building, University of Tsukuba
Access	Take a bus bound for "Tsukuba Daigaku Chuo" or the "University Loop-line On-campus Bus [Tsukuba Daigaku Junkan Bus]" and get off at Oikoshi Gakusei Shukusha Mae
Speaker	Dr. Masahiko Watanabe Department of Anatomy, Faculty of Medicine, Hokkaido University
Subject	"Glyoxal, an innovative fixative for neuroscience research"
Summary	Synaptic molecules are highly organized to fulfill neural functions. Through my neuroanatomical research on molecular organization and mechanism of glutamatergic synaptic wiring, I realize that widely-used formalin fixation often hinders synaptic molecules from histochemical detection. This is particularly true for PSD and synaptic adhesion molecules. To solve this problem, I have so far tested and adopted various antigen-retrieval and -exposing techniques, such as protease pretreatment and postembedding methods. Recently, glyoxal fixation was reported to be a better alternative for formalin fixation (Richter et al. EMBO J 37:139-159, 2018). In this seminar, I will introduce the usefulness and effectiveness of the new fixative in synaptic molecule detection. Click here for more information: http://wpi-iiis.tsukuba.ac.jp/seminar
Contact	International Institute for Integrative Sleep Medicine Phone: 029-853-8080 (ext.8080)